| Overview |
| bs-7703R-Cy3 |
| TSPYL5 Polyclonal Antibody, Cy3 Conjugated |
| FCM, IF(IHC-P), IF(IHC-F), IF(ICC) |
| Mouse |
| Human, Horse, Rabbit |
| Specifications |
| Cy3 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human TSPYL5 |
| 251-350/417 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 85453 |
| Q86VY4 |
| Nucleus |
| Testis-specific Y-encoded-like protein 5; TSPY-like protein 5; TSPYL5; KIAA1750 |
| Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7. |
| Application Dilution |
| FCM |
1:20-100 |
| IF(IHC-P) |
1:50-200 |
| IF(IHC-F) |
1:50-200 |
| IF(ICC) |
1:50-200 |
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