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CCDC11 Polyclonal Antibody, FITC Conjugated

Applications

  • WB
  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Human
  • Mouse
  • Rat
  • Others

Predicted Reactivity

  • Cow
  • Horse
Overview
Catalog # bs-7740R-FITC
Product Name CCDC11 Polyclonal Antibody, FITC Conjugated
Applications WB, IF(IHC-P), IF(IHC-F), IF(ICC)
Specificity Due to the similarity of this protein to RWD domain-containing protein 1, there is a chance that this antibody will react with this protein based on a 75% non-sequential amino acid similarity.
Reactivity Human, Mouse, Rat, Others
Predicted Reactivity Cow, Horse
Specifications
Conjugation FITC
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CCDC11
Immunogen Range 331-430/514
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 220136
Swiss Prot Q96M91
Subcellular location Cytoplasm, Nucleus
Synonyms HTX6; CCDC11; Coiled-coil domain-containing protein 11
Background CCDC11 is a 514 amino acid protein encode by a gene that maps to human chromosome 18q21.1. Encoding over 300 genes, chromosome 18 contains about 76 million bases. Trisomy 18, or Edwards syndrome, is the second most common trisomy after Downs syndrome. Symptoms of Edwards syndrome include low birth weight, a variety of physical development defects, heart deformations and breathing difficulty. Translocation between chromosome 18 and 14 is the most common translocation in cancers, and occurs in follicular lymphomas. Niemann-Pick disease, hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18. The TGF modulators, Smad2, Smad4 and Smad7 are encoded by chromosome 18.
Application Dilution
WB 1:300-5000
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200