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CCDC11 Polyclonal Antibody, AbBy Fluor-647 Conjugated

Applications

  • WB
  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Human
  • Mouse
  • Rat

Predicted Reactivity

  • Cow
  • Horse
Overview
Catalog # bs-7740R-BF647-100uL
Product Name CCDC11 Polyclonal Antibody, AbBy Fluor-647 Conjugated
Applications
WB IF(IHC-P) IF(IHC-F) IF(ICC)
Specificity Due to the similarity of this protein to RWD domain-containing protein 1, there is a chance that this antibody will react with this protein based on a 75% non-sequential amino acid similarity.
Reactivity Human, Mouse, Rat
Predicted Reactivity Cow, Horse
Specifications
Conjugation AbBy Fluor-647
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CCDC11
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 220136
Swiss Prot Q96M91
Subcellular location Cytoplasm, Nucleus
Synonyms HTX6; CCDC11; Coiled-coil domain-containing protein 11
Background CCDC11 is a 514 amino acid protein encode by a gene that maps to human chromosome 18q21.1. Encoding over 300 genes, chromosome 18 contains about 76 million bases. Trisomy 18, or Edwards syndrome, is the second most common trisomy after Downs syndrome. Symptoms of Edwards syndrome include low birth weight, a variety of physical development defects, heart deformations and breathing difficulty. Translocation between chromosome 18 and 14 is the most common translocation in cancers, and occurs in follicular lymphomas. Niemann-Pick disease, hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18. The TGF modulators, Smad2, Smad4 and Smad7 are encoded by chromosome 18.
Application Dilution
WB 1:300-5000
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Frequently asked questions

Which applications is CCDC11 Polyclonal Antibody, AbBy Fluor-647 Conjugated (bs-7740R-BF647) validated for, and at what dilution?

bs-7740R-BF647 is validated for WB (1:300-5000); IF(IHC-P) (1:50-200); IF(IHC-F) (1:50-200); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does CCDC11 Polyclonal Antibody, AbBy Fluor-647 Conjugated (bs-7740R-BF647) react with?

Tested reactivity: Human, Mouse, Rat. Predicted reactivity (expected from sequence homology but not yet tested): Cow, Horse.

How should bs-7740R-BF647 be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise CCDC11 Polyclonal Antibody, AbBy Fluor-647 Conjugated (bs-7740R-BF647)?

KLH conjugated synthetic peptide derived from human CCDC11

What are the excitation and emission wavelengths of the AbBy Fluor-647 conjugate (bs-7740R-BF647)?

AbBy Fluor-647 on bs-7740R-BF647: excitation / emission 650nm/665nm.

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US only. One sample per paid order, subject to review. Backorders may ship separately. Confirm Free at checkout. Check application and species suitability; same target does not guarantee equivalent performance. For research use only.

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