AICDA Polyclonal Antibody
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-7855R-100uL |
| Product Name | AICDA Polyclonal Antibody |
| Applications |
WB
ELISA
IHC-F
IF(IHC-P)
IF(IHC-F)
IF(ICC)
IHC-P
|
| Reactivity | Human |
| Predicted Reactivity | Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human AICDA |
| Immunogen Range | 101-198/198 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 57379 |
| Swiss Prot | Q9GZX7 |
| Subcellular location | Nucleus |
| Synonyms | AID; ARP2; CDA2; HIGM2; HEL-S-284; Single-stranded DNA cytosine deaminase; Activation-induced cytidine deaminase; Cytidine aminohydrolase; AICDA |
| Background | Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class-switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. |
| Application Dilution | |
| WB | 1:500-1000 |
| ELISA | 1:200-400 |
| IHC-F | 1:50-200 |
| IF(IHC-P) | 1:50-200 |
| IF(IHC-F) | 1:50-200 |
| IF(ICC) | 1:50-200 |
| IHC-P | 1:100-500 |
Frequently asked questions
Which applications is AICDA Polyclonal Antibody (bs-7855R) validated for, and at what dilution?
bs-7855R is validated for WB (1:500-1000); ELISA (1:200-400); IHC-F (1:50-200); IF(IHC-P) (1:50-200); IF(IHC-F) (1:50-200); IF(ICC) (1:50-200); IHC-P (1:100-500). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does AICDA Polyclonal Antibody (bs-7855R) react with?
Tested reactivity: Human. Predicted reactivity (expected from sequence homology but not yet tested): Mouse, Rat.
How should bs-7855R be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise AICDA Polyclonal Antibody (bs-7855R)?
KLH conjugated synthetic peptide derived from human AICDA Immunogen range: 101-198/198.