CNIH2/3 Polyclonal Antibody

Applications

  • WB
  • ELISA
  • IHC-P
  • IHC-F
  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Rat

Predicted Reactivity

  • Human
  • Mouse
  • Dog
  • Cow
  • Pig
  • Horse
  • Rabbit
Overview
Catalog # bs-8027R
Product Name CNIH2/3 Polyclonal Antibody
Applications WB, ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
Specificity This antibody detects both CNIH2 and CNIH3 proteins
Reactivity Rat
Predicted Reactivity Human, Mouse, Dog, Cow, Pig, Horse, Rabbit
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CNIH2/CNIH3
Immunogen Range 25-120/160
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 254263; 149111
Swiss Prot Q6PI25; Q8TBE1
Subcellular location Cytoplasm, Cell membrane
Synonyms Protein cornichon homolog 2; CNIH2; Cornichon family AMPA receptor auxiliary protein 2; Protein cornichon homolog 3; CNIH3; Cornichon family AMPA receptor auxiliary protein 3
Background CNIH2 and CNIH3 regulate the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). They promote their targeting to the cell membrane and synapses and modulate their gating properties by regulating their rates of activation, deactivation and desensitization. CNIH2 also blocks CACNG8-mediated resensitization of AMPA receptors.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200