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UMPS Polyclonal Antibody, Biotin Conjugated

Applications

  • WB
  • ELISA
  • IHC-P
  • IHC-F

Reactivity

  • Human

Predicted Reactivity

  • Mouse
  • Rat
  • Dog
  • Cow
  • Sheep
  • Horse
  • Rabbit
  • Monkey
Overview
Catalog # bs-8110R-Biotin
Product Name UMPS Polyclonal Antibody, Biotin Conjugated
Applications WB, ELISA, IHC-P, IHC-F
Reactivity Human
Predicted Reactivity Mouse, Rat, Dog, Cow, Sheep, Horse, Rabbit, Monkey
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human UMPS
Clonality Polyclonal
Clone # #REF!
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C for 12 months.
Target
Gene ID 7372
Swiss Prot P11172
Subcellular location Cytoplasm
Synonyms Uridine 5'-monophosphate synthase; UMPS; UMP synthase; Orotate phosphoribosyltransferase; OPRT; OPRTase; ODC; OMPdecase; OK/SW-cl.21
Background This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500