AP-18
| Overview | |
| Catalog # | bs-82082c-10mg |
| Product Name | AP-18 |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | RT |
| Target | |
| Product Information | TRPA1 channel blocker IC50=3.1-4.5 μM in various cell lines. Reduces cinnamaldehyde-induced nociception in vivo and blocks cold- and mustard oil-induced activation of mouse TRPA1 but not capsaicin-induced activation. Does not block TRPV1, V2, V3, V4 or M8 at concentrations up to 50 μM.1 Blocks TRPA1 pore dilation (IC50=10.3 μM).2 An important tool for assessing the role of TRPA1 in cell signaling and physiological processes.3-5 |
| Description | CAS Number: 55224-94-7 Chemical Name: 4-(4-Chlorophenyl)-3-methylbut-3-en-2-oxime Molecular weight: 209.67 Formula: C11H12ClNO Solubility: DMSO (25 mg/ml) Ethanol (25 mg/ml) Physical Properties: White solid Purity: 98% by TLC [10% Methanol in methylene chloride, Rf = 0.60] NMR Conforms |
Frequently asked questions
Which applications is AP-18 (bs-82082C) validated for, and at what dilution?
bs-82082C is validated for Life Science( N/A).
How should bs-82082C be stored?
RT Storage buffer: White solid