Methotrexate

Overview
Catalog #	bs-82146c-100mg
Product Name	Methotrexate
Specifications
Storage Buffer	Yellow solid
Storage Condition	-20°C
Target
Product Information	A synthetic folic acid analog with immunosuppressant and cancer chemotherapeutic activity.1 Inhibits thymidylate synthetase and de novo purine synthesis.2,3 Displays beneficial effects in rheumatoid arthritis by inhibiting the production of cytokines induced by T-cell activation4 and stimulation of adenosine release5. It is the classic disease-modifying antirheumatic drug (DMARD).6
Description	CAS Number: 133073-73-1 Chemical Name: N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid Molecular weight: 683.63 Formula: C20H22N8O5·xH2O Solubility: DMSO (45 mg/ml) Physical Properties: Yellow solid Purity: 98% by HPLC NMR (conforms)