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LDN-57444

Overview
Catalog # bs-82166c-5mg
Product Name LDN-57444
Specifications
Storage Buffer Yellow solid
Storage Condition -20°C
Target
Product Information Inhibits ubiquitin C-terminal hydrolase (UCH-L1) (Ki=0.4 M). Decreases proteasome activity and increases levels of ubiquitinated proteins. Induces apoptosis. Causes dramatic alterations in synaptic protein distribution and spine morphology in vivo. Cell permeable.
Description CAS Number: 668467-91-2

Chemical Name: 5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-2,3-dione 3-(O-acetyloxime)

Molecular weight: 397.65

Formula: C17H11Cl3N2O3

Solubility: DMSO (20 mg/ml)

Physical Properties: Yellow solid

Purity: 98% by TLC, NMR conforms