BI-6015
| Overview | |
| Catalog # | bs-82222c-5mg |
| Product Name | BI-6015 |
| Specifications | |
| Storage Buffer | Tan solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Hepatocyte nuclear factor 4α (HNF4α) antagonist. HNF4α is a central regulator of gene expression in cell types that play a central role in metabolic homeostasis. 1 BI-6015 binds to HNF4α with high affinity and modulates the expression of known target genes. It was shown to be selectively cytotoxic to cancer cell lines in vitro and in vivo however in vivo potency was limited by suboptimal pharmacokinetics. 2 Represents the first small molecule tool for pharmacologic modulation of HNF4α activity. 2 Cell permeable. |
| Description | CAS Number: 93987-29-2 Chemical Name: 2-Methyl-1-[(2-methyl-5-nitrophenyl)sulfonyl]-1H-benzimidazole Molecular weight: 331.35 Formula: C15H13N3O4S Solubility: DMSO (25 mg/ml) Ethanol (10 mg/ml) Physical Properties: Tan solid Purity: 98% by TLC, NMR (Conforms) |
Frequently asked questions
Which applications is BI-6015 (bs-82222C) validated for, and at what dilution?
bs-82222C is validated for Life Science( N/A).
How should bs-82222C be stored?
-20°C Storage buffer: Tan solid