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Daminozide

Overview
Catalog # bs-82223c-50mg
Product Name Daminozide
Specifications
Storage Buffer White solid
Storage Condition RT
Target
Product Information A selective inhibitor of the KDM2/7 JmjC subfamily of histone demethylases. IC50=1.5, 0.55 and 2.1 μM for KDM2A, PHF8 and KDM7A respectively. Highly selective over other subfamily members (KDM3, KDM4, KDM5 and KDM6) as well as other 2-oxoglutarate oxygenases (FIH, PHD2 and BBOX1), IC50>100 μM1.
Description CAS Number: 1596-84-5

Chemical Name: 1-(2,2-Dimethylhydrazide)butanedioic acid

Molecular weight: 160.17

Formula: C6H12N2O3

Solubility: DMSO (50 mg/ml), water (20 mg/ml)

Physical Properties: White solid

Purity: 98% by TLC, NMR (Conforms)