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LM22A-4

Overview
Catalog # bs-82224c-5mg
Product Name LM22A-4
Specifications
Storage Buffer White solid
Storage Condition -20°C
Target
Product Information Small molecule BDNF mimetic displaying neurotrophhic activity. Partial agonist at TRKB and activates TRKB signaling. In in vitro models of neurodegenerative disease, it prevented neuronal degeneration with equal efficacy to that of BDNF. After in vivo administraton, it caused hippocampal and striatal TrkB activation in mice and improved motor learning after traumatic brain injury in rats1. Improves respiratory function in a mouse models of Rett syndrome2.
Description CAS Number: 37988-18-4

Chemical Name: N,N’N’ Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide

Molecular weight: 339.35

Formula: C15H21N3O6

Solubility: DMSO (50 mg/ml) Water (50 mg/ml)

Physical Properties: White solid

Purity: 98% by TLC, NMR (Conforms)

Frequently asked questions

Which applications is LM22A-4 (bs-82224C) validated for, and at what dilution?

bs-82224C is validated for Life Science( N/A).

How should bs-82224C be stored?

-20°C Storage buffer: White solid