ML241
| Overview | |
| Catalog # | bs-82317c-5mg |
| Product Name | ML241 |
| Specifications | |
| Storage Buffer | Pale yellow solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Potent and selective p97 AAA ATPase inhibitor, IC50=100 nM. Inhibits degradation of a p97-dependent but not p97-independent proteasome substrate in a dual-reporter cell line1. It impairs the endoplasmic reticulum-associated degradation (ERAD) pathway.1 ML241 and related inhibitors (DBeQ for example) have differential responses to p97 mutants as well as the presence of cofactors suggesting the possibility of context-dependent p97 inhibitors.2,3 |
| Description | CAS Number: 1346528-06-0 Chemical Name: N-Benzyl-2-(2,3-dihydro-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydroquinazolin-4-amine Molecular weight: 372.46 Formula: C23H24N4O Solubility: DMSO (50 mg/ml) Ethanol (14 mg/ml) Physical Properties: Pale yellow solid Purity: 98% by HPLC NMR (conforms) |
Frequently asked questions
Which applications is ML241 (bs-82317C) validated for, and at what dilution?
bs-82317C is validated for Life Science( N/A).
How should bs-82317C be stored?
-20°C Storage buffer: Pale yellow solid