ST-034307
| Overview | |
| Catalog # | bs-82351c-5mg |
| Product Name | ST-034307 |
| Specifications | |
| Storage Buffer | Yellow solid |
| Storage Condition | RT |
| Target | |
| Product Information | A novel selective adenylyl cyclase 1 (AC1) inhibitor, IC50=2.3 μM . Inhibits calcium2+-stimulated cAMP accumulation in HEK cells stably transfected with AC11. It was also shown to inhibit AC1 stimulated by forskolin- and Gαs-coupled receptors in HEK-AC1 cells. It enhanced μ-opioid receptor-mediated inhibition of AC1 but it blocked heterologous sensitization of AC1 caused by chronic μ-opioid receptor activation.1 Displays analgesic properties in a mouse model of inflammatory pain.1 |
| Description | CAS Number: 133406-29-8 Chemical Name: 6-Chloro-2-(trichloromethyl)-4H-1-benzopyran-4-one Molecular weight: 297.95 Formula: C10H4Cl4O2 Solubility: DMSO (30 mg/ml) Ethanol (6 mg/ml) Physical Properties: Yellow solid Purity: 98% by TLC, NMR (Conforms) |
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