Cerulenin
| Overview | |
| Catalog # | bs-82373c-5mg |
| Product Name | Cerulenin |
| Specifications | |
| Storage Buffer | Off-white solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Fatty acid synthase (FAS) inhibitor. Binds to β-keto-acyl-ACP synthase (KAS; IC50=1.5 μM), thus inhibiting protein acylation at concentrations of 45-134 μM1. Produces metabolic effects similar to the effects of leptin, but through mechanisms that are independent of, or down-stream of, both leptin and melanocortin receptors2. Reduces nutrient-induced insulin release from normal rat islets3. Induces apoptosis in human melanoma A-375 cells4. |
| Description | CAS Number: 17397-89-6 Chemical Name: 2,3-Epoxy-4-oxo-7,10-dodecadienamide Molecular weight: 223.27 Formula: C12H17NO3 Solubility: DMSO (10 mg/ml) Ethanol (10 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC, NMR (Conforms) |
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