Thiolutin
| Overview | |
| Catalog # | bs-82392c-1mg |
| Product Name | Thiolutin |
| Specifications | |
| Storage Buffer | Yellow solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Inhibits the deubiquitinating (DUB) activity of PSMD14 exhibiting potent antitumor activity in neck squamous cell carcinoma in vitro and in vivo1. Inhibits endothelial cell adhesion by perturbing HSP27 interactions with components of the actin and intermediate filament cytoskeleton2. Potently inhibits developmental angiogenesis in zebrafish2. Inhibits adhesion of endothelial cells to vitronectin (IC50=0.83 M) inhibiting tumor cell-induced angiogenesis in vivo3. Cell permeable. Active in vivo. |
| Description | CAS Number: 87-11-6 Chemical Name: N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)acetamide Molecular weight: 228.29 Formula: C8H8N2O2S2 Solubility: DMSO (15 mg/ml) Physical Properties: Yellow solid Purity: 98% by HPLC NMR (Conforms) |
Frequently asked questions
Which applications is Thiolutin (bs-82392C) validated for, and at what dilution?
bs-82392C is validated for Life Science( N/A).
How should bs-82392C be stored?
-20°C Storage buffer: Yellow solid