Bexarotene
| Overview | |
| Catalog # | bs-82399c-10mg |
| Product Name | Bexarotene |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | A highly potent and selective retinoid X receptor (RXR) agonist (EC50=28, 25, 20 nM for RXRα, β, γ respectively)1. Clinically useful antineoplastic agent for cutaneous T-cell lymphoma2 Causes complete regression of mammary carcinoma3. Bexarotene significantly increases clearance of soluble β-amyloid in a mouse Alzheimer′s model and increases cognitive ability4. Reverses apoE4-driven brain pathology and behavioral deficits in vivo5. |
| Description | CAS Number: 153559-49-0 Chemical Name: 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid Molecular weight: 348.49 Formula: C24H28O2 Solubility: DMSO (60 mg/ml) Ethanol (10 mg/ml) Physical Properties: White solid Purity: 98% by TLC, NMR (Conforms) |
Frequently asked questions
Which applications is Bexarotene (bs-82399C) validated for, and at what dilution?
bs-82399C is validated for Life Science( N/A).
How should bs-82399C be stored?
-20°C Storage buffer: White solid