Ansamitocin P3
| Overview | |
| Catalog # | bs-82432c-1mg |
| Product Name | Ansamitocin P3 |
| Specifications | |
| Storage Buffer | Yellow solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Ansamitocin P3 (66547-09-9) is a fungal metabolite from Actinosynnema pretiosum which binds to the phomopsin A/rhizoxin site on tubulin1,2. Ansamitocin P3 is a maytansine analog which displays potent cytotoxicity against various human tumor cell lines2,3. Maytansine and its analogs cause extensive disassembly of microtubules and totally prevent tubulin spiralization4. |
| Description | CAS Number: 66547-09-9 Chemical Name: Molecular weight: 635.16 Formula: C32H43ClN2O9 Solubility: DMSO (50 mg/ml) Ethanol (30 mg/ml) Physical Properties: Yellow solid Purity: >90% by TLC [1:9 CH3OH:CH2Cl2, Rf = 0.54] remainder is P-1, P-2 and P-4. NMR (Conforms) |
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