L-Cycloserine
| Overview | |
| Catalog # | bs-82450c-100mg |
| Product Name | L-Cycloserine |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | L-Cycloserine down-regulates sphingolipid biosynthesis via inhibition of serine palmitoyltransferase (3-ketodihydrosphingosine synthetase).1 The L isomer was shown to be 100-fold more potent than the D isomer at inhibition of the brain microsomal enzyme.1 It is a useful pharmacological agent for lowering sphingolipid levels in cells2 as well as in animal models3. Inhibition of de novo ceramide biosynthesis with L-cycloserine positively affected the senescent phenotype, restoring neuronal signaling and reducing mitochondrial dysfunction in a cortical neuronal model of senescence.4 |
| Description | CAS Number: 339-72-0 Chemical Name: (S)-4-Amino-3-isoxaolidinone Molecular weight: 102.09 Formula: C3H6N2O2 Solubility: DMSO (20 mg/ml) with warming, Water (25 mg/ml) Physical Properties: White solid Purity: 98% by TLC, NMR (Conforms) |
Frequently asked questions
Which applications is L-Cycloserine (bs-82450C) validated for, and at what dilution?
bs-82450C is validated for Life Science( N/A).
How should bs-82450C be stored?
-20°C Storage buffer: White solid