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DHRS4 Polyclonal Antibody, FITC Conjugated

Applications

  • WB

Reactivity

  • Mouse

Predicted Reactivity

  • Human
  • Rat
Overview
Catalog # bs-8264R-FITC-100uL
Product Name DHRS4 Polyclonal Antibody, FITC Conjugated
Applications
WB
Reactivity Mouse
Predicted Reactivity Human, Rat
Specifications
Conjugation FITC
Host Rabbit
Source KLH conjugated synthetic peptide derived from human DHRS4
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 10901
Subcellular location Cytoplasm, Nucleus
Synonyms NDRD; RRD; AI043103; AI790593; Carbonyl reductase; CR; D14Ucla2; Dehydrogenase/reductase SDR family member 4; Dhrs4; DHRS4_HUMAN; humNRDR antibody NADPH dependent carbonyl reductase/NADP retinol dehydrogenase; NADPH dependent retinol dehydrogenase/reductase; NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase; NADPH-dependent retinol dehydrogenase/reductase; NRDR; Peroxisomal short chain alcohol dehydrogenase; Peroxisomal short-chain alcohol dehydrogenase; PHCR; PRO1800; PSCD; SCAD-SRL; SCADSRL; Short chain dehydrogenase/reductase family member 4; Short-chain dehydrogenase/reductase family member 4; UNQ851.
Background Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones.Tissue specificity:Isoform 1 is predominantly expressed in normal cervix (at protein level). Isoform 4 is expressed in some neoplastic cervical tissues, but not in normal cervix (at protein level). Isoform 5 and isoform 6 are expressed in a few neoplastic cervical tissues.
Application Dilution
WB 1:300-5000

Frequently asked questions

Which applications is DHRS4 Polyclonal Antibody, FITC Conjugated (bs-8264R-FITC) validated for, and at what dilution?

bs-8264R-FITC is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does DHRS4 Polyclonal Antibody, FITC Conjugated (bs-8264R-FITC) react with?

Tested reactivity: Mouse. Predicted reactivity (expected from sequence homology but not yet tested): Human, Rat.

How should bs-8264R-FITC be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise DHRS4 Polyclonal Antibody, FITC Conjugated (bs-8264R-FITC)?

KLH conjugated synthetic peptide derived from human DHRS4

What are the excitation and emission wavelengths of the FITC conjugate (bs-8264R-FITC)?

FITC on bs-8264R-FITC: excitation / emission 494nm/518nm.