Canagliflozin
| Overview | |
| Catalog # | bs-82692c-10mg |
| Product Name | Canagliflozin |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Potent inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), IC50 = 2.2 nM selective over SGLT1, IC50=910 nM.1 Dose dependently increases glucose excretion in healthy subjects.2 Displays beneficial effects in nonalcoholic fatty liver disease (NAFLD).3 Extends lifespan in male but not female mice.4 Inhibits cancer cell proliferation via inhibition of mitochondrial complex-1 supported respiration.5 Suppresses the growth of pancreatic cancer cells.6 |
| Description | CAS Number: 842133-18-0 Chemical Name: (1S)-1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol Molecular weight: 444.52 Formula: C24H25FO5S Solubility: DMSO (40 mg/ml) Physical Properties: White solid Purity: 98% by TLC NMR (Conforms) |
Frequently asked questions
Which applications is Canagliflozin (bs-82692C) validated for, and at what dilution?
bs-82692C is validated for Life Science( N/A).
How should bs-82692C be stored?
-20°C Storage buffer: White solid