NLRP3i
| Overview | |
| Catalog # | bs-82701c-20-mg |
| Product Name | NLRP3i |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | RT |
| Target | |
| Product Information | NLRP3 inflammasome inhibitor which likely acts via interfering with the formation of the NLRP3 inflammasome complex and which exhibits promising in vivo protective activities in mouse acute myocardial infarction models. It blocks ASC aggregation, blocks the release of IL-1 and the activation of caspase-1 in macrophages expressing constitutively active NLRP3 but does not directly inhibit caspase-1.1,2 Limits infarct size after myocardial ischemia-reperfusion as well as leukocyte infiltration in a peritonitis model in mice.2 |
| Description | CAS Number: 16673-34-0 Chemical Name: 4-[2-(5-Chloro-2-methoxybenzamido)ethyl]phenylsulfonamide Molecular weight: 368.84 Formula: C16H17ClN2O4S Solubility: DMSO (45 mg/ml) Physical Properties: White solid Purity: 98% by TLC NMR (Conforms) |
Frequently asked questions
Which applications is NLRP3i (bs-82701C) validated for, and at what dilution?
bs-82701C is validated for Life Science( N/A).
How should bs-82701C be stored?
RT Storage buffer: White solid