UPF-1069

Overview
Catalog #	bs-82710c-5mg
Product Name	UPF-1069
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	A selective PARP-2 inhibitor (IC50=0.3 µM and ~ 27-fold selective against PARP-1).1,2 Increases apoptosis in hippocampal slices but protects cortical cells in models of post-ischemic brain damage.3 Blocks the interaction between PARP-2 and FOXA1, attenuating androgen receptor-mediated gene expression and inhibiting androgen receptor-positive prostate cancer growth.4
Description	CAS Number: 1048371-03-4 Chemical Name: 5-(2-Oxo-3-phenylethoxy)-1(2H)-isoquinolinone Molecular weight: 279.29 Formula: C17H13NO3 Solubility: DMSO (40 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC, NMR (Conforms)