EN450
| Overview | |
| Catalog # | bs-82736c-5mg |
| Product Name | EN450 |
| Specifications | |
| Storage Buffer | White to off-white solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | EN450 is a molecular glue that covalently interacts with a cysteine residue on the E2 ubiquitin ligase UBE2D. It displayed anti-proliferative effects in HAP1 leukemia cells. EN450s antiproliferative effects were elicited via proteasome-dependent degradation of nuclear factor kappa B subunit 1(NFkB1).1 |
| Description | CAS Number: 793719-01-4 Chemical Name: N-(2-Chloro-5-(N,N-dimethylsulfamoyl)phenyl)acrylamide Molecular weight: 288.75 Formula: C11H13ClN2O3S Solubility: DMSO (>80 mg/ml) Physical Properties: White to off-white solid Purity: >98% by HPLC , NMR (Conforms) |
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