GIMAP8 Polyclonal Antibody, Biotin Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-8274R-Biotin-100uL |
| Product Name | GIMAP8 Polyclonal Antibody, Biotin Conjugated |
| Applications |
WB
ELISA
IHC-P
IHC-F
|
| Reactivity | Mouse |
| Predicted Reactivity | Human, Rat, Horse, Rabbit |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human GIMAP8 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C for 12 months. |
| Target | |
| Gene ID | 155038 |
| Swiss Prot | Q8ND71 |
| Subcellular location | Cytoplasm |
| Synonyms | GTPase IMAP family member 8; hIAN6; Human immune associated nucleotide 6; IAN9; IANT; Immune associated nucleotide; Immune-associated nucleotide-binding protein 9; Protein IanT; GIMA8_HUMAN. |
| Background | The GTPase of the immunity-associated protein (GIMAP) family of proteins include seven members that are expressed by genes residing on human chromosome 7. GIMAP proteins have been implicated in the regulation of lymphomyeloid cell survival. GIMAP8, also known as IAN9 (immune-associated nucleotide-binding protein 9) or IANT, is a 665 amino acid protein that localizes to Golgi apparatus, Endoplasmic reticulum and mitochondria. Suggested to have an anti-apoptotic effect on the immune system, GIMAP8 plays a role in infection response and is encoded by a gene that maps to human chromosome 7q36.1. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. |
| Application Dilution | |
| WB | 1:300-5000 |
| ELISA | 1:500-1000 |
| IHC-P | 1:200-400 |
| IHC-F | 1:100-500 |
Frequently asked questions
Which applications is GIMAP8 Polyclonal Antibody, Biotin Conjugated (bs-8274R-Biotin) validated for, and at what dilution?
bs-8274R-Biotin is validated for WB (1:300-5000); ELISA (1:500-1000); IHC-P (1:200-400); IHC-F (1:100-500). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does GIMAP8 Polyclonal Antibody, Biotin Conjugated (bs-8274R-Biotin) react with?
Tested reactivity: Mouse. Predicted reactivity (expected from sequence homology but not yet tested): Human, Rat, Horse, Rabbit.
How should bs-8274R-Biotin be stored?
Store at -20C for 12 months. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise GIMAP8 Polyclonal Antibody, Biotin Conjugated (bs-8274R-Biotin)?
KLH conjugated synthetic peptide derived from human GIMAP8