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LNT 1

Overview
Catalog # bs-82774c-5mg
Product Name LNT 1
Specifications
Storage Buffer Off-white solid
Storage Condition -20°C
Target
Product Information Potent (IC50 = 11 nM) inhibitor of flap endonuclease 1 (FEN1).1 It showed similar potency in inhibiting exonuclease 1 (EXO1).2 Induces a DNA damage response and ultimately cell death. FEN1 inhibitors have therapeutic potential for the treatment of cancers that are defective for homologous repair and other DNA repair and DNA damage checkpoint pathways.4
Description CAS Number: 824983-91-7

Chemical Name: 1-(2,3-Dihydro-1,4-benzodioxin-3-ylmethyl)-3-hydroxythieno[3,2-d]pyrimidine-2,4-dione

Molecular weight: 332.33

Formula: C15H12N2O5S

Solubility: DMSO (15 mg/ml)

Physical Properties: Off-white solid

Purity: 98% by TLC , NMR (Conforms)

Frequently asked questions

Which applications is LNT 1 (bs-82774C) validated for, and at what dilution?

bs-82774C is validated for Life Science( N/A).

How should bs-82774C be stored?

-20°C Storage buffer: Off-white solid