Siramesine
| Overview | |
| Catalog # | bs-82822c-5mg |
| Product Name | Siramesine |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Siramesine (Lu 28-179) is a 2 selective agonist (IC50’s: 1 = 17nM, 2 = 0.2nM).1 It produced non-sedating potent and long-last anxiolytic effects in rodents.2 Siramesine induced caspase-independent programmed cell death in various cancer cell lines via increased levels of ROS and lysosomal leakage.3,4,5 Mitochondrial destabilization via loss of membrane potential and increased ROS has also been offered as a mechanism of action for the triggering of cell death by Siramesine.6 |
| Description | CAS Number: 147817-50-3 Chemical Name: 1’-[4-[1-(4-Fluorophenyl)indol-3-yl]butyl]spiro[1H-2-benzofuran-3,4’-piperidine; Molecular weight: 454.59 Formula: C30H31FN2O Solubility: DMSO (>25 mg/ml) Physical Properties: White solid Purity: 98% by HPLC NMR (Conforms) |
Frequently asked questions
Which applications is Siramesine (bs-82822C) validated for, and at what dilution?
bs-82822C is validated for Life Science( N/A).
How should bs-82822C be stored?
-20°C Storage buffer: White solid