Harmine HCl
| Overview | |
| Catalog # | bs-82893c-25mg |
| Product Name | Harmine HCl |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Selective competitive and reversible inhibitor of MAO-A (IC50 = 8 µM).1 Harmine is a potent and specific inhibitor of both the kinase activity and autophosphorylation of tyrosine during translation DYRK1A (IC50’s: DYRKA1A = 33 nM; DYRKA1B = 166 nM; DYRK2 = 1.9 µM; DYRK4 = 80 µM).2,3 Inhibits self-renewal and promotes differentiation of glioblastoma stem-like cells(GSLC’s) possibly via inhibition of Akt phosphorylation.4 Harmine has also been shown to possess antimicrobial, antifungal, antiplasmodial, antitumor, antioxidant, antimutagenic and antigenotoxic properties.5 Inhibits osteoclast differentiation and bone resorption via downregulation of c-Fos and NFATc1 induced by RANKL.6 |
| Description | CAS Number: 343-27-1 Chemical Name: 7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole hydrochloride Molecular weight: 248.71 Formula: C13H12N2O·HCl Solubility: Water (25 mg/ml) Physical Properties: White solid Purity: >98% (TLC: 10% Methanol/methylene chloride + 0.5% NH4OH; Rf = 0.50) |
Frequently asked questions
Which applications is Harmine HCl (bs-82893C) validated for, and at what dilution?
bs-82893C is validated for Life Science( N/A).
How should bs-82893C be stored?
-20°C Storage buffer: White solid