UNC1999

Overview
Catalog #	bs-82908c-5mg
Product Name	UNC1999
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	UNC1999 is an orally bioavailable, highly selective inhibitor of both wild-type and mutant EZH1 and EZH2 lysine methyltransferases (IC50’s = 45 nM and 2 nM respectively).1 Inhibition of EZH2 with UNC1999 enhanced the efficacy of gefitinib in suppressing the proliferation of colon cancer cells
Description	CAS Number: 1431612-23-5 Chemical Name: N-[(6-methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-1-propan-2-yl-6-[6-(4-propan-2-ylpiperazin-1-yl)pyridin-3-yl]indazole-4-carboxamide Molecular weight: 569.74 Formula: C33H43N7O2 Solubility: DMSO (10 mg/ml) Physical Properties: White solid Purity: 98% by HPLC, NMR (Conforms)