Atglistatin

Overview
Catalog #	bs-82937c-5mg
Product Name	Atglistatin
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	Atglistatin is the first small molecule inhibitor of adipose triglyceride lipase (ATGL) – IC50 = 700 nM.1 It exhibits high selectivity for ATGL, is active in vitro and in vivo, and does not inhibit other key metabolic lipases. ATGL is the rate limiting enzyme in lipolysis and is thus an excellent target to reduce fatty acid mobilization and decrease lipotoxicity in metabolic syndrome. Inhibition of ATGL may be a useful strategy to attack the increased metabolic rate of cancerous cells.2
Description	CAS Number: 1469924-27-3 Chemical Name: N’-[4’-(Dimethylamino)[1,1’-biphenyl]-3-yl]-N,N,-dimethylurea Molecular weight: 283.37 Formula: C17H21N3O Solubility: DMSO (5 mg/ml) Ethanol (5 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC, NMR (Conforms)