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PF-9366

Overview
Catalog # bs-82960c-5mg
Product Name PF-9366
Specifications
Storage Buffer Beige solid
Storage Condition -20°C
Target
Product Information PF-9366 is an allosteric inhibitor (IC50 = 420 nM) of methionine adenosyltransferase 2A (Mat2A), the primary enzyme responsible for extrahepatic synthesis of S-adenosyl-L-methionine (SAM).1 It inhibited cellular SAM production in H520 lung and Huh-7 liver cancer cells with IC50’s of 1.2 µM and 225 nM respectively.
Description CAS Number: 72882-78-1

Chemical Name: 2-(7-Chloro-5-phenyl)-[1,2,4]triazolo[4,3-a]quinoline-1-yl)-N,N,dimethylethanamine

Molecular weight: 350.85

Formula: C20H19ClN4

Solubility: DMSO (20 mg/ml)

Physical Properties: Beige solid

Purity: 98% by TLC NMr (Conforms)

Frequently asked questions

Which applications is PF-9366 (bs-82960C) validated for, and at what dilution?

bs-82960C is validated for Life Science( N/A).

How should bs-82960C be stored?

-20°C Storage buffer: Beige solid