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SM-88

Overview
Catalog # bs-82965c-10mg
Product Name SM-88
Specifications
Storage Buffer Off-white solid
Storage Condition RT
Target
Product Information A “dysfunctional” tyrosine mimetic. It is taken up by cancer cells and disrupts tyrosine-mediated metabolic pathways including synthesis of the important protein mucin-1 leading to oxidative stress.1 In clinical trials with melanin, phenytoin, and sirolimus (SMK therapy) for use in advanced metastatic cancer2, in combination with methoxsalen, phenytoin, and sirolimus (MPS therapy) for prostate cancer3, and as monotherapy for metastatic pancreatic cancer4. It is also an inhibitor of tyrosine hydroxylase resulting in a reduction of catecholamines and their metabolites.5
Description CAS Number: 30625-05-9

Chemical Name: 2-Amino-3-(4-hydroxyphenyl)-2-methylpropionic acid hydrochloride

Molecular weight: 231.68

Formula: C10H13NO3·HCl

Solubility: DMSO (>50 mg/ml) Ethanol (>35 mg/ml)

Physical Properties: Off-white solid

Purity: >98% by TLC (NMR Conforms)

Frequently asked questions

Which applications is SM-88 (bs-82965C) validated for, and at what dilution?

bs-82965C is validated for Life Science( N/A).

How should bs-82965C be stored?

RT Storage buffer: Off-white solid