BO-264
| Overview | |
| Catalog # | bs-82989c-5mg |
| Product Name | BO-264 |
| Specifications | |
| Storage Buffer | Off-white solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | BO-264 is a potent (IC50 = 188 nM) inhibitor of transforming acidic coiled-coil 3 (TACC3), an important protein involved in microtubule stability and centrosome integrity.1 TACC3 is frequently upregulated in a broad range of cancers. BO-264 displayed significant anticancer activity in greater than 90% of cell lines in the NCI-60 human cancer cell line panel. Active in vivo in mice injected with JIMT-1 and EMT6 breast cancer cells as well as mouse colon cancer xenografts HCT-116 and CT-26. |
| Description | CAS Number: 2408648-20-2 Chemical Name: 3-(4-Methoxyphenyl)-N-(2-morpholin-4-ylpyrimidin-4-yl)-1,2-oxazol-5-amine Molecular weight: 353.38 Formula: C18H19N5O3 Solubility: DMSO (>25 mg/ml) Physical Properties: Off-white solid Purity: 99% by HPLC NMR (Conforms) |
Frequently asked questions
Which applications is BO-264 (bs-82989C) validated for, and at what dilution?
bs-82989C is validated for Life Science( N/A).
How should bs-82989C be stored?
-20°C Storage buffer: Off-white solid