Selonsertib

Overview
Catalog #	bs-82994c-5mg
Product Name	Selonsertib
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Potent Apoptosis signal-regulating kinase 1 (ASK1) inhibitor (pIC50 = 8.3)1 found to improve metabolic parameters in nonalcoholic steatohepatitis, reduce hepatic steatosis, inflammation, and fibrosis2-4. Selonsertib suppressed the efflux function of multidrug resistance (MDR) transporters ABCB1 and ABCG2.5
Description	CAS Number: 1448428-04-3 Chemical Name: 5-(4-Cyclopropylimidazol-1-yl)-2-fluoro-4-methyl-N-[6-(4-propan-2-yl)-1,2,4-triazol-3-yl)pyridine-2-yl]benzamide Molecular weight: 445.5 Formula: C24H24FN7O Solubility: DMSO (>25 mg/ml) Physical Properties: White solid Purity: 98% by HPLC NMR (Conforms)