TXNRD1 Polyclonal Antibody, APC Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-8299r-apc-100uL |
| Product Name | TXNRD1 Polyclonal Antibody, APC Conjugated |
| Applications |
WB
IF
FLOW-CYT
|
| Reactivity | Human, Mouse, Rat |
| Predicted Reactivity | Dog, Cow, Pig, Horse |
| Specifications | |
| Conjugation | APC |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human TXNRD1 |
| Immunogen Range | 451-550/649 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 7296 |
| Swiss Prot | Q16881 |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | TR; TR1; TXNR; TRXR1; GRIM-12; Thioredoxin reductase 1, cytoplasmic; Gene associated with retinoic and interferon-induced mortality 12 protein; Gene associated with retinoic and IFN-induced mortality 12 protein; KM-12-derived reductase-like factor; Thioredoxin reductase TR1; TXNRD1; GRIM12; KDRF |
| Background | Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid. |
| Application Dilution | |
| WB | 1:500-1000 |
| IF | 1:50-200 |
| Flow-Cyt | 1:50-200 |
Frequently asked questions
Which applications is TXNRD1 Polyclonal Antibody, APC Conjugated (bs-8299R-APC) validated for, and at what dilution?
bs-8299R-APC is validated for WB (1:500-1000); IF (1:50-200); Flow-Cyt (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does TXNRD1 Polyclonal Antibody, APC Conjugated (bs-8299R-APC) react with?
Tested reactivity: Human, Mouse, Rat. Predicted reactivity (expected from sequence homology but not yet tested): Dog, Cow, Pig, Horse.
How should bs-8299R-APC be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise TXNRD1 Polyclonal Antibody, APC Conjugated (bs-8299R-APC)?
KLH conjugated synthetic peptide derived from human TXNRD1 Immunogen range: 451-550/649.
What are the excitation and emission wavelengths of the APC conjugate (bs-8299R-APC)?
APC on bs-8299R-APC: excitation / emission 650nm/660nm.