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LDN-192960 HCl

Overview
Catalog # bs-83043c-5mg
Product Name LDN-192960 HCl
Specifications
Storage Buffer Yellow solid
Storage Condition -20°C
Target
Product Information LDN-192960 is a potent inhibitor of Haspin (IC50 = 10 nM), DYRK2 (IC50 = 2 nM), and DYRK3 (IC50 = 19 nM).1,2 It induced cytotoxicity and growth inhibition in multiple myeloma and triple negative breast cancer cells and triple negative breast cancer mouse allo/xenografts via partial inhibition of 26S proteasome activity.3
Description CAS Number: 184582-62-5

Chemical Name: 3-(2,7-Dimethoxyacridin-9-yl)sulfanylpropan-1-amine dihydrochloride

Molecular weight: 401.35

Formula: C18H20N2O2S·2HCl

Solubility: DMSO (>25 mg/ml) Water (2 mg/ml)

Physical Properties: Yellow solid

Purity: >98% by HPLC NMR (Conforms)

Frequently asked questions

Which applications is LDN-192960 HCl (bs-83043C) validated for, and at what dilution?

bs-83043C is validated for Life Science( N/A).

How should bs-83043C be stored?

-20°C Storage buffer: Yellow solid