Cantharidin

Overview
Catalog #	bs-83135c-100mg
Product Name	Cantharidin
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Inhibits protein phosphatase 2A (Ki=0.19 μM) and PP1 (Ki=1.1 μM)1. Displays >500-fold selectivity over PP2B. Suppresses growth and migration of PANC-1 pancreatic cancer cells via phosphorylation and degradation of β-catenin2. Arrests G2/M transition via JNK/Sp1-dependent down-regulation of CDK13. Cell permeable. Warning: Avoid skin contact, may cause skin irritation or blistering.
Description	CAS Number: 56-25-7 Chemical Name: Phosphatase PP2A inhibitor Molecular Weight: 196.20 Formula: C10H12O4 Solubility: DMSO (20 mg/ml) Ethanol (5 mg/ml) Physical Properties: White solid Purity: 98% by TLC [5% methanol/methylene chloride; Rf = 0.40] NMR (Conforms)