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5-Azacytidine

Overview
Catalog # bs-83175c-50mg
Product Name 5-Azacytidine
Specifications
Storage Buffer White solid
Storage Condition -20°C
Target
Product Information Specific inhibitor of DNA methyltransferase1. Incorporates into DNA and covalently reacts with and inhibits DNA methyltransferases. Induces demethylation and reactivation of silenced genes2. Increases stem cell reprogramming efficiency3. Induces cardiac differentiation of human mesenchymal stem cells by activating ERK4. Induces apoptosis in multiple myeloma cells via ATR-mediated DNA double strand breaks5. Cell permeable.
Description CAS Number: 320-67-2

Chemical Name: DNA hypomethylation agent

Molecular Weight: 244.21

Formula: C8H12N4O5

Solubility: DMSO (25 mg/ml) Water (12 mg/ml)

Physical Properties: White solid

Purity: 98% by TLC, NMR (conforms)