Hydroxychloroquine sulfate

Overview
Catalog #	bs-83198c-50mg
Product Name	Hydroxychloroquine sulfate
Specifications
Storage Buffer	White solid
Storage Condition	RT
Target
Product Information	Hydroxychloroquine sulfate is a lysosomotropic agent which inhibits autophagy and triggers apoptosis in a variety of cell types.1,2 Augments the anticancer activity of DNA-damaging chemotherapy.3 Antiinflammatory activity. Decreases cell surface expression of TNFα receptors in U937 cells.4 Hydroxychloroquine sulfate has been used to treat alopecia successfully5 and is a clinically useful antimalaria agent. Cell permeable and active in vivo.
Description	CAS Number: 747-36-4 Chemical Name: Autophagy inhibitor Molecular Weight: 433.96 Formula: C18H26ClN3O · H2SO4 Solubility: water (40mg/ml) DMSO (nil) Physical Properties: White solid Purity: 98% by TLC, NMR (Conforms)