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PP2

Overview
Catalog # bs-83206c-25mg
Product Name PP2
Specifications
Storage Buffer Off-white solid
Storage Condition -20°C
Target
Product Information Potent and selective Src family kinase inhibitor. Inhibits Lck(IC50=4 nM); Fyn (IC50=5 nM); Hck (IC50=5 nM). It displays weak inhibition of EGFR (IC50=480 nM) and no inhibition of ZAP-70 (IC50> 100 μM) and JAK2 (IC50> 50 μM)1. It is a useful probe for exploring the involvement of Src family kinases in signal transduction pathways2.
Description CAS Number: 172889-27-9

Chemical Name: Src family kinase inhibitor

Molecular Weight: 301.78

Formula: C15H16ClN5

Solubility: DMSO (25 mg/ml) Ethanol (3 mg/ml)

Physical Properties: Off-white solid

Purity: 98% by TLC, NMR (Conforms)