Apicidin
| Overview | |
| Catalog # | bs-83228c-5mg |
| Product Name | Apicidin |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Apicidin is a fungal toxin that is a potent, cell permeable inhibitor of histone deacetylases (HDAC’s).1 It also displays antitumor properties by inducing changes in p21WAF1/Cip1 and gelsolin gene expression causing cell cycle arrest in the G1 phase.2 Apicidin dramatically decreases HIF-1α protein levels and transcriptional activity in human and mouse tumor cell lines.3 |
| Description | CAS Number: 183506-66-3 Chemical Name: HDAC inhibitor Molecular Weight: 623.78 Formula: C34H49N5O6 Solubility: DMSO (1 mg/ml) Physical Properties: White solid Purity: >98% |