SB 203580
| Overview | |
| Catalog # | bs-83266c-25mg |
| Product Name | SB 203580 |
| Specifications | |
| Storage Buffer | Off-white solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | A potent and selective inhibitor of p38 MAP kinase, IC50=50 and 500 nM for p38 and p38β2 respectively. No other kinases (in a panel of 30) were significantly inhibited including p38γ and δ at 10 μM2. A potent inhibitor of inflammatory cytokine production (IC50=15-25 mg/kg in mice and rats) in animal models of arthritis, bone resorption, endotoxin shock and immune function3. |
| Description | CAS Number: 152121-47-6 Chemical Name: p38 MAP kinase inhibitor Molecular Weight: 377.44 Formula: C21H16N3OSF Solubility: DMSO (100 mg/ml) Ethanol (10 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC, NMR (conforms) |
Frequently asked questions
Which applications is SB 203580 (bs-83266C) validated for, and at what dilution?
bs-83266C is validated for Life Science( N/A).
How should bs-83266C be stored?
-20°C Storage buffer: Off-white solid