Metformin HCl
| Overview | |
| Catalog # | bs-83305c-25g |
| Product Name | Metformin HCl |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | RT |
| Target | |
| Product Information | Clinically useful antidiabetic agent. Lowers plasma glucose levels and improves insulin sensitivity. Inhibits hepatic gluconeogenesis by activation of the AMP-activated protein kinase (AMPK) pathway.1,2 Displays antiproliferative and pro-apoptotic actions in a variety of cancer cell lines.3,4 Induces autophagy via inhibition of the mTOR pathway. Activates PGC1 and improves mitochondrial dynamics in renal tubular cells.5 Upregulates SIRT1 activity in endothelial cells.6 Neuroprotective and lowers -synuclein phosphorylation in the Parkinson’s disease MPTP mouse model.7 |
| Description | CAS Number: 1115-70-4 Chemical Name: Anti-diabetic agent Molecular Weight: 165.63 Formula: C4H11N5 · HCl Solubility: DMSO (8 mg/ml) Water (16 mg/ml Physical Properties: White solid Purity: 98%, NMR (Conforms) |
Frequently asked questions
Which applications is Metformin HCl (bs-83305C) validated for, and at what dilution?
bs-83305C is validated for Life Science( N/A).
How should bs-83305C be stored?
RT Storage buffer: White solid