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Oridonin

Overview
Catalog # bs-83320c-25mg
Product Name Oridonin
Specifications
Storage Buffer White of off-white solid
Storage Condition -20°C
Target
Product Information A potent, covalent inhibitor of the NLRP3 inflammasome with anti-inflammatory activity in various mouse models.1 Inhibits vascular inflammation in vivo.2 Inhibits aberrant AKT activation in human breast cancer cells with hyperactivated PI3K/AKT signaling.3 Inhibits migration, invasion and adhesion of melanoma cells.4 Induces apoptosis in osteosarcoma cells by multiple pathways.5
Description CAS Number: 28957-04-2

Chemical Name: HSP70 inhibitor

Molecular Weight: 364.43

Formula: C20H28O6

Solubility: DMSO (50 mg/ml) Ethanol (10 mg/ml)

Physical Properties: White of off-white solid

Purity: 98% by TLC NMR (conforms)