Blebbistatin

Overview
Catalog #	bs-83337c-25mg
Product Name	Blebbistatin
Specifications
Storage Buffer	Yellow solid
Storage Condition	-20°C
Target
Product Information	Blebbistatin is a potent, selective, reversible, cell-permeable inhibitor of non-muscle myosin II (IC50 ~4 mM).1,2 During cell division it inhibits contraction of the cleavage furrow without disrupting mitosis.1 Blocks cell blebbing (hence its name) and rapidly disrupts directed cell migration and cytokinesis in many cell types.1 It promotes neurite outgrowth3 and is neuroprotective against vincristine-induced neurotoxicity in iPSC-derived neurons4.
Description	CAS Number: 674289-55-5 Chemical Name: Non-muscle myosin II inhibitor Molecular Weight: 292.34 Formula: C18H16N2O2 Solubility: DMSO (45 mg/ml) Physical Properties: Yellow solid Purity: >98% by TLC NMR (Conforms)