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Blebbistatin

Overview
Catalog # bs-83337c-25mg
Product Name Blebbistatin
Specifications
Storage Buffer Yellow solid
Storage Condition -20°C
Target
Product Information Blebbistatin is a potent, selective, reversible, cell-permeable inhibitor of non-muscle myosin II (IC50 ~4 mM).1,2 During cell division it inhibits contraction of the cleavage furrow without disrupting mitosis.1 Blocks cell blebbing (hence its name) and rapidly disrupts directed cell migration and cytokinesis in many cell types.1 It promotes neurite outgrowth3 and is neuroprotective against vincristine-induced neurotoxicity in iPSC-derived neurons4.
Description CAS Number: 674289-55-5

Chemical Name: Non-muscle myosin II inhibitor

Molecular Weight: 292.34

Formula: C18H16N2O2

Solubility: DMSO (45 mg/ml)

Physical Properties: Yellow solid

Purity: >98% by TLC NMR (Conforms)

Frequently asked questions

Which applications is Blebbistatin (bs-83337C) validated for, and at what dilution?

bs-83337C is validated for Life Science( N/A).

How should bs-83337C be stored?

-20°C Storage buffer: Yellow solid