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Ophiobolin

Overview
Catalog # bs-83348c-1mg
Product Name Ophiobolin
Specifications
Storage Buffer White solid
Storage Condition -20°C
Target
Product Information Selectively inhibits the growth of cancer cells (IC50=0.4-4.3 M) over normal cells (IC50=20.9 M).1 Induces non-apoptotic cell death in glioblastoma cells and is active in an in vivo model.2 Covalently reacts with primary amines such as lysine side chains2 and phosphatidylethanolamine3 forming unique pyrrole adducts. Induces ER stress4, paraptosis4 and autophagy5.
Description CAS Number: 4611-05-6

Chemical Name: Autophagy inducer / Anticancer

Molecular Weight: 400.55

Formula: C25H36O4

Solubility: DMSO (10 mg/ml)

Physical Properties: White solid

Purity: 98% by HPLC NMR (Conforms)

Frequently asked questions

Which applications is Ophiobolin (bs-83348C) validated for, and at what dilution?

bs-83348C is validated for Life Science( N/A).

How should bs-83348C be stored?

-20°C Storage buffer: White solid