XL413·HCl
| Overview | |
| Catalog # | bs-83383c-25mg |
| Product Name | XL413·HCl |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | XL413 is a potent (IC50 = 4.8 nM) ATP-competitive inhibitor of the important DNA replication initiation kinase Cdc7 (DDK).1 It increases the efficiency of homology directed DNA repair in CRISPR-Cas9 gene editing.2 XL413 acted synergistically with other chemotherapy agents in various cancer models.3-5 |
| Description | CAS Number: 2062200-97-7 Chemical Name: Cdc7 inhibitor/CRISPR enhancer Molecular Weight: 326.18 Formula: C14H12N3O2·HCl Solubility: DMSO (2 mg/ml with warming); water (7 mg/ml with warming) Physical Properties: White solid Purity: >98% by HPLC NMR (Conforms) |
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