CR8 3HCl (R)
| Overview | |
| Catalog # | bs-83440c-25mg |
| Product Name | CR8 3HCl (R) |
| Specifications | |
| Storage Buffer | White or off-white solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Second generation analog of roscovitine which inhibits cyclin-dependent kinases with increased potency, Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk5, p25, and Cdk9/cyclin T, IC50s=0.09, 0.072, 0.041, 0.11 and 0.18 M respectively.1,2 Acts as a molecular glue degrader that depletes cyclin K.3 CR8 displays neuroprotective effects in various models including traumatic brain injury.4 |
| Description | CAS Number: 294646-77-8 Chemical Name: CDK inhibitor Molecular Weight: 540.91 Formula: C24H29N7O ∙3HCl Solubility: DMSO (30 mg/ml) Physical Properties: White or off-white solid Purity: 98% by HPLC NMR (Conforms) |
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