CaCCinh-A01
| Overview | |
| Catalog # | bs-83588c-5-mg |
| Product Name | CaCCinh-A01 |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | CaCCInh-A01 is a potent inhibitor of TMEM16A (IC50 = 2.1 mM), a calcium-activated chloride channel1. Blockade of TMEM16A with CaCCInh-A01 protects against renal fibrosis2, reduces blood brain barrier permeability, attenuates brain infarct size and neurological deficits after ischemic stroke3, and induces apoptosis and cell cycle arrest in various epithelium-originated cancer cells4. |
| Description | CAS Number: 407587-33-1 Chemical Name: 6-(1,1-Dimethylethyl)-2-[(2-furanylcarbonyl)amino]-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid Molecular Weight: 347.43 Formula: C18H21NO4S Solubility: DMSO (40 mg/ml) Physical Properties: White solid Purity: >98% by TLC, NMR (Conforms) |
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