KLHDC8A Polyclonal Antibody, PE-Cy7 Conjugated
Applications
Predicted Reactivity
| Overview | |
| Catalog # | bs-8358R-PE-Cy7-100uL |
| Product Name | KLHDC8A Polyclonal Antibody, PE-Cy7 Conjugated |
| Applications |
WB
|
| Predicted Reactivity | Human, Mouse, Rat, Cow, Pig, Rabbit |
| Specifications | |
| Conjugation | PE-Cy7 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human KLHDC8A |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 55220 |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | Kelch domain containing 8A; Kelch domain containing protein 8A; KLHDC 8A; MGC19056; RGD1305132; A630065K24Rik; FLJ10748; KLD8A_HUMAN. |
| Background | Kelch domain-containing protein 8A (KLHDC8A) is a 350 amino acid protein. KLHDC8A contains seven kelch repeats, each of which is an approximately 50 amino acid long conserved region that forms a tertiary structure beta-propeller. The gene that encodes KLHDC8A is located on chromosome 1, which is the largest human chromosome, spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes Lamin A. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is KLHDC8A Polyclonal Antibody, PE-Cy7 Conjugated (bs-8358R-PE-Cy7) validated for, and at what dilution?
bs-8358R-PE-Cy7 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
How should bs-8358R-PE-Cy7 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise KLHDC8A Polyclonal Antibody, PE-Cy7 Conjugated (bs-8358R-PE-Cy7)?
KLH conjugated synthetic peptide derived from human KLHDC8A
What are the excitation and emission wavelengths of the PE-Cy7 conjugate (bs-8358R-PE-Cy7)?
PE-Cy7 on bs-8358R-PE-Cy7: excitation / emission 488nm/780nm.